Grants (Ongoing)

Dr. Rahul Kumar (Co-PI)

Project Title: Microsatellite instability across various tumor types diagnostic criteria, methods of detection and bio-clinical associations

Month/Year : 2024-2027

Amount:1.8 Cr

Dr.Anindya Roy

Funding Agency:SERB


Project Title: Understanding the mechanism of degradation of cytoplasmic DNA containing alkyl-adducts

Month/Year : 2023-2026

Amount:64.4 lakhs

Dr. Rajakumara Eerappa

Funding Agency: STARS-MoE


Project Title:Mechanistic and structural studies on the allosteric regulation of phospho-mimetic variants of poly(ADP-ribose) polymerases

Month/Year : 2023

Amount: 94 Lakhs

Dr.Anamika Bhargava

Funding Agency: ICMR


Title:An experimental study of calcium channel expression and calcium dynamics in cells derived from Indian breast cancer patients

Month/Year: 2023-2026

Amount: 53.01 Lakhs

Dr.Ashish Misra

Funding Agency:Indian Council of Medical Research (ICMR)


Project Title: Targeting the Splicing and Stability of Androgen Receptor Splice Variants in Castration-Resistant Prostate Cancer

Month/Year : 2023-2026

Amount:18.1 lakhs

Dr.Ashish Misra

Funding Agency:SERB-CRG


Project Title:Targeting CDC-like kinase 1 to overcome drug resistance in Castration Resistant Prostate Cancer

Month/Year : 2023 - 2026

Amount: To be sanctioned, approved

Dr. Gunjan Mehta

Funding Agency:JICA FRIENDSHIP 2


Project Title: Role of chromatin remodelers in meiotic recombination and transcriptional switch during yeast meiosis.

Month/Year : 2023; 2 years

Amount: 20 Lakhs

Dr. Sandipan Ray

Funding Agency:ICMR, Ad-hoc


Project Title: Investigation on the Cross-talk among Circadian Aberrations, Sleep Deficiency, Aging, and DNA Damage for Potential Health and Therapeutic Benefits

Month/Year: 2023-2026

Amount:87.5 Lakhs

Dr. Sandipan Ray (Co-PI)

Funding Agency: SERB-SUPRA


Project Title: Nano-Transformable Hydrogel for Targeted ChemoImmunotherapy of Breast Cancer

Month/Year : 2023-2026

Amount: 79.13 lakhs

Dr. Sandipan Ray (Co-PI)

Funding Agency: Wellcome Trust


Project Title: Validation of a translatable chronobiological signature of early relapse in bipolar disorder (Co-PI, Lead from India in this multi-national project)

Month/Year :2023-2028

Amount: 2224 lakhs

Dr. Thenmalarchelvi Ratinavelan

Funding Agency:SERB


Project Title: Exploring the mechanistic role of Saccharomyces cerevisiae Stm1 protein in apoptosis-like cell death

Month/Year : 2023-2026

Amount: 3.07 lakhs

Dr. Thenmalarchelvi Ratinavelan (Co-PI)

Funding Agency: BNRS


Project Title:Development of 3D printable antimicrobial composite hydrogels with metal-binding peptides for anti-inflammatory effects for bone tissue engineering

Month/Year :2023-2026

Amount: 33.976lakhs

Dr.Abhishek Subramanian

Funding Agency: DBT, Ramalingaswami Re-entry Fellowship/contigency


Project Title:Computational approaches to discover host-parasite metabolic interactions in human microeukaryotic parasite infections of the gut and lung

Month/Year: 2023 -28

Amount:52.5 lakhs

Dr. Himanshu Joshi

Funding Agency: Startup Research Grant (SRG) Science and Engineering Research Board


Project Title: Computational exploration of membrane spanning DNA nanostructures for cellular drug delivery

Amount: 26 lakhs

Dr. Himanshu Joshi

Funding Agency: Understanding DNA-Based Naonstructures using Molecular Simulation


Project Title: DST-Inspire fellowship

Month/Year : 2022-2027

Amount: 35 lakhs

Dr.Anamika Bhargava

Funding Agency: Sai life sciences


Project Title: Consultancy project on Electrophysiology.

Month/Year : 2022-2023

Amount: 1.53 lakhs

Dr.Anamika Bhargava

Funding Agency: SOCH-IITH


Project Title: Game-changing low-cost, accurate and user-friendly patch-clamp microfluidic chip-based system for measurement of ion-channel activity in live biological cells

Month/Year : 2022-2024

Amount: 35 Lakhs

Dr.Anindya Roy

Funding Agency: DBT


Project Title: Molecular Characterisation of anti-HIV drug Ritonavir as an inhibitor of DNA alkylation repair protein

Month/Year : 2022-2025

Amount:17.4 Lakhs

Dr. Gaurav Sharma (Co-PI)

Funding Agency:Indian Council of Medical Research (ICMR)


Project Title:A systems biology approach to define the host response in SARS-CoV-2 induced multisystem inflammatory syndrome in children (MIS-C) with neurological manifestations

Month/Year :2022-2025

Amount: 49 lakhs

Dr. Sandipan Ray (Co-PI)

Funding Agency:SOCH, IITH


Project Title: In-Situ Nano-transformable hydrogel for affordable targeted therapy of highly metastatic cancers

Month/Year: 2022-2024

Amount: 100 Lakhs

Dr. Rajakumara Eerappa

Funding Agency: DBT, Extramural


Project Title: Mechanistic understanding of functioning of Chd1 remodelers using biochemical, structural and single-molecule imaging appraoches

Month/Year :2022-25

Amount: 54.76 Lakhs

Dr. Gunjan Mehta (Co-PI)

Funding Agency: DBT, Extramural


Project Title: Mechanistic understanding of functioning of Chd1 remodelers using biochemical, structural and single-molecule imaging appraoches

Month/Year :2022-25

Amount: 54.76 Lakhs

Dr. Basant Kumar Patel

Funding Agency: DST-SERB


Project Title: Investigation of dependence of cytotoxicity of caspase cleaved TDP-25, TDP-35 and alternate spliced TDP-43-S1 and TDP-43-S-2 fragments of TDP-43 on the IRE1 pathway of the ER stress response mechanism in the TDP-43 proteinopathy models of amyotrophic lateral sclerosis disease.

Month/Year : 2021-2024

Amount: 54.59

Dr. Anamika Bhargava (Co-PI)

Funding Agency: ICMR-DHR

Project Title: ICMR-DHR centre of excellence (Sub project: Development of zebrafish preclinical model for breast cancer)

Month/Year :2021-2024

Amount: 1500 Lakhs

Dr. Gunjan Mehta

Funding Agency:DBT, Innovative Young Biotechnologist Award

Project Title: Elucidating the role of chromatin remodelers in yeast meiosis, especially in meiotic recombination, chromosome segregation and transcription of meiosis-specific genes.

Month/Year :2021; 3 years

Amount: 61.624 Lakhs

Dr. Anamika Bhargava(Co-PI)

Funding Agency: SERB DST


Project Title: Investigation of dependence of cytotoxicity of caspase-cleaved TDP-25, TDP-35 and alternate spliced TDP-43-S! and TDP-43-S-2 fragments of TDP-43 on the IRE! pathway of the ER stress response mechanism in the TDP-43 proteinopathy models of amyotrophic lateral sclerosis disease.

Month/Year : 2021-2024

Amount: 54.6 Lakhs

Dr. Gunjan Mehta

Funding Agency: DBT, Ramalingaswami Re-entry Fellowship/contigency


Project Title: Exploring the cohesin ring independent functions of Rec8 during yeast meiosis.

Month/Year : 2021; 5 years

Amount: 42.5 Lakhs

Dr.N.K.Raghavendra

Funding Agency: DBT


Title:Characterization of human E2 enzyme Ube2N response to DNA

Month/Year: 2021; 3 years

Amount: 37.8 Lakhs

Dr. Rajakumara Eerappa

Funding Agency: DST-SERB, CRG


Title:Structure based design and evaluation of inhibitors against phosphodiesterases for enhancing sperm motility and early embryo development, and to reduce

Month/Year:2021-24

Amount: 41.39 Lakhs

Dr. Sandipan Ray

Funding Agency: SRG-SERB


Project Title:Comprehensive Characterization of the Circadian Regulations of Kinases and Diverse Signaling Pathway

Month/Year : 2021-2023

Amount: 28.71 Lakhs

Dr. Gaurav Sharma

Funding Agency: Department of Science and Technology (DST)-INSPIRE


Project Title: Microbiome of Critically Endangered Traditional Indian Medicinal (CETIM) plants: Conservation and Biomedical Research

Month/Year : 2019-24

Amount: 35 Lakhs

Dr. Thenmalarchelvi Ratinavelan

Funding Agency: BIRAC-SRISTI-AWARD


Project Title: Revelation of G-quadruplex formation as a molecular basis of fragile X tremor/ataxia syndrome (FXTAS) leads to a new direction in the drug discovery

Month/Year :2019-on going

Amount: 15 lakhs